BREATHE Program · Defense Health

Autonomous biosecurity for the facilities that protect America's defenders.

R-TRAC is deploying qPCR-based biosensors and automated building operating systems across Defense Health Agency medical centers — safeguarding military personnel and the immunocompromised patients they serve.

Led by SafeTraces · ARPA-H BREATHE Program

The Challenge

9.5 million people rely on the Defense Health Agency system. Their facilities need to see what's in the air.

Defense Health Agency medical centers serve active-duty military, their families, and veterans — including large populations of immunocompromised patients undergoing treatment whose vulnerability to airborne exposures is acute.

These facilities operate under continuous patient load, across diverse climates and building types. Most cannot detect what's circulating in their air — much less respond to it automatically.

R-TRAC is building the autonomous sensing, risk assessment, and building control infrastructure to change that across the DHA network.

700+ military hospitals and clinics

The Defense Health Agency operates one of the largest healthcare networks in the United States — serving 9.5 million beneficiaries across hundreds of facilities.

"Like a smoke detector for what's in the air"

Most buildings have no idea what biological organisms are circulating in their air. R-TRAC gives defense health facilities that awareness — and the ability to act on it automatically.

The Approach

From detection to building response — fully automated.

PathogenSentinel™ biosensor

A microarray qPCR biosensor using a unique positional printing method to detect a broad spectrum of organisms. SafeTraces' platform — a spinout of Lawrence Livermore National Laboratories — provides rapid, autonomous detection without manual intervention.

Risk-triggered building operating modes

Software that activates specialized building operating modes when airborne risk escalates — automatically adjusting ventilation, filtration, and air treatment to protect occupants before exposures accumulate.

Multi-partner integration platform

R-TRAC integrates technology from eight organizations — including Siemens for building systems, Ginkgo Bioworks for biosensing, and Stanford and Penn State for scientific validation.

From SafeTraces

R-TRAC in action

Video coming soon

Deployment

Active across major Defense Health Agency medical centers

Maryland

Walter Reed National Military Medical Center, Bethesda — the flagship military medical center serving senior military leadership and their families.

Texas

Brooke Army Medical Center, San Antonio — the largest military hospital in the United States.

Washington

Madigan Army Medical Center, Joint Base Lewis-McChord — serving the Pacific Northwest military community.

Partners

An eight-organization team

SafeTraces Siemens Ginkgo Bioworks Gate Scientific Stanford University Penn State University Uniformed Services University (USU)
Team

Led by SafeTraces

Erik Malmstrom

CEO, SafeTraces. SafeTraces is a dual-use technology company focused on predicting, detecting, and preventing biological threats through autonomous environmental biosecurity. A spinout of Lawrence Livermore National Laboratories.

Read the SafeTraces announcement ↗
In the News

Coverage of R-TRAC

PR Newswire

SafeTraces Selected as Prime Performer for ARPA-H BREATHE Program

Official SafeTraces announcement of the R-TRAC award

Hoover Institution

Seeing Through the Molecular Curtain

An in-depth look at SafeTraces' biosecurity technology and its applications

ARPA-H

ARPA-H R-TRAC Award Page

Official ARPA-H program overview for the R-TRAC team

Interested in defense health partnership?

R-TRAC is building autonomous air biosecurity for defense health facilities. If your organization works within the Defense Health Agency system or federal healthcare, we'd like to connect.

defense@breathe2026.org